TABLE 4

Quality of the Body of Evidence for Each Outcome Using GRADE

Does Enteroviral Testing Reduce Resource Use?
Starting Level of QualityaDowngradeUpgradeFinal Level of Quality
BiasInconsistentIndirectImprecisePublication BiasLarge EffectDose ResponseDirection of Confounding
2 plus ⊕⊕○○−100000+102 plus ⊕⊕○○
Should EV Testing Be Performed in Absence of Pleocytosis?
2 plus ⊕⊕○○−10000+1002 plus ⊕⊕○○
  • a Evidence quality is rated as high (4 plus, ⊕⊕⊕⊕), moderate (3 plus, ⊕⊕⊕○), low (2 plus, ⊕⊕○○), or very low (1 plus, ⊕○○○) using GRADE.