TABLE 2

Number of Troughs Within the Range of 15–20 μg/mL

Dose (mg/kg per day)2–23 mo (%)2–5 y (%)6–12 y (%)13–17 y (%)Total (%)
<450/10 (0)1/11 (9.1)1/12 (8.3)3/12 (25)5/45 (11.1)
500/4 (0)0/9 (0)0/4 (0)0/2 (0)0/19 (0)
600/10 (0)0/25 (0)1/21 (4.8)2/7 (28.6)3/63 (4.8)
700/3 (0)1/11 (9.1)0/7 (0)1/21 (4.8)
>750/2 (0)0/4 (0)2/4 (50)0/1 (0)2/11 (18.2)
Total0/29 (0)2/60 (3.3)4/48 (8.3)5/22 (22.7)11/159 (6.9)