Contraindications to Pharmacologic Prophylaxis23,37,42

Absolute contraindications:
 • Bleeding disorder, known or tendency
 • Evidence of or high risk of hemorrhage
 • Platelet count unable to be sustained >50 000/mm3
Relative contraindications
 • Intracranial mass
 • Lumbar puncture or epidural catheter removal in previous 12 h
 • Neurosurgical procedure
 • Pelvic fracture within past 48 h
 • Uncontrolled hypertension