TABLE 2

Interventions Performed and Clinical Outcomes of Bronchiolitis Patients on HFNC Admitted to the PICU Before and After Implementation of HFNC on the General Pediatric Wards (N = 290)

Before (n = 120)After (n = 170)P
Diagnostic testing, n (%)
 RSV positive61/96 (63.5)55/102 (53.9).17
 Chest radiograph94/119 (79.0)109/170 (64.1).006
Therapeutic interventions
 Mean Max HFNC rate (L/min)9.0 (SD 2.5 L) (95% CI 8.6–9.5)7.4 (SD 2.2 L) (95% CI 7.0–7.7)<.001
 Mean days of HFNC2.4 (SD 1.4) (95% CI 2.2–2.7)1.8 (SD 1.4) (95% CI 1.6–2.0)<.001
 Intubation, n (%)9/120 (7.5)11/170 (6.5).73
 Bronchodilator use, n (%)101/120 (84.2)137/170 (80.6).43
Clinical outcomes
 Median total LOS (d)4 (IQR 3–5)3 (IQR 2–4)<.001
 Median total hospital charges$12 257 (IQR 8365–17 226)$9337 (IQR 6882–12 624)<.001a
 APR-DRG severity level1.6 (SD 0.6) (95% CI 1.5–1.7)2.1 (SD 0.8) (95% CI 2.0–2.2)<.001
 Transfer to wards on HFNC, n (%)0/120 (0)51/170 (30.0)<.001
 Transfer back to PICU, n (%)6/120 (5.0)5/170 (2.9).37
 30-d readmission, n (%)11/120 (9.2)13/170 (7.7).64
  • APR-DRG: 1 = minor to 4 = extreme. CI, confidence interval.

  • a Difference in total hospital charges is no longer significant after controlling for LOS.