TABLE 1

Demographics and Clinical Characteristics

All Evaluated Patients (n = 248)Non-VLR Admissions (n = 219)VLR Admissions (n = 20)VLR Discharges (n = 6)Non-VLR Discharges (n = 3)P
Age in mo, median (IQR)2 (1, 29)2 (1, 17)54 (5, 118)95 (71, 193)2 (1, 2)<.01
Female, n (%)100 (40)87 (40)12 (60)1 (17)0.09
ED LOS in hr, median (IQR)6.2 (5.2, 7.4)6.1 (5.1, 7.3)7.5 (6.1, 8.9)5.9 (5.2, 6.6)6.5 (6.2, 6.5).03
Bacterial meningitis, n (%)8 (3)8 (4)000.99
Enterovirus meningitis, n (%)28 (11)22 (10)5 (25)1 (17)0.17
Enterovirus season,a n (%)119 (48)97 (44)15 (75)5 (83)2 (67).01
Peripheral WBC (K/μL), geometric mean (SD)11.6 (1.6)11.9 (1.6)9.6 (1.5)8.6 (1.5)9.0 (1.8).07
Peripheral ANC (K/μL), geometric mean (SD)4.4 (2.4)4.4 (2.4)4.9 (2.0)5.2 (1.4)1.4 (2.1).18
CSF WBC (mm3), geometric mean (SD)71 (5)70 (5)93 (5)79 (3)24 (3).44
CSF ANC (K/μL), geometric mean (SD)7 (22)7.2 (23)7.6 (25)15.9 (4.3)4.0 (4).82
CSF protein (mg/dL), geometric mean (SD)89 (3) [n = 243]97 (3) [n = 214]42 (2)53 (1)148 (5)<.01
CSF glucose (mg/dL), mean (SD)48 (15) [n = 244]48 (16) [n = 215]52 (9)54 (3)51 (13).20
  • IQR, interquartile range; LOS, length of stay; WBC, white blood cell count.

  • P values based on Kruskal–Wallis test for continuous variables and Fisher’s exact test for categorical variables.

  • Peripheral WBC, peripheral ANC, CSF WBC, CSF ANC, and CSF protein were natural logarithm transformed to obtain normal distributions.

  • a Enterovirus season is June–October.