TABLE 2

Primary Outcome Measures by Randomized Feeding Group (Intention to Treat)

Outcome MeasuresStandard-Calorie FormulaHigh-Calorie FormulaPa
Mean (SD)Median (Range)Mean (SD)Median (Range)
Days to weight nadirN = 22N = 27
5.05 (2 to 8)4.44 (2 to 8).20
Days to return to birth wtN = 20bN = 26b
14.714.5 (9 to 21)13.614 (8 to 20).08
Maximum weight loss, %c−9.4 (2.6)−9.7 (−13.8 to −5.1)−8.6 (2.3)−9.2 (−13.6 to −3.6).15
Average daily weight gain after return to birth wt, %d0.67 (0.69)0.43 (0.01 to 3.7)0.81 (0.65)0.70 (0.01 to 3.3).11
  • a Time to event data statistics is based on log-rank statistics.

  • b Two infants from the standard-calorie group and 1 infant from the high-calorie group were lost to follow-up before returning to birth weight and were excluded from that analysis.

  • c Based on longitudinal estimates excluding day of life.

  • d Maximum percent weight loss (or gain) statistics are based on t tests with assumed equal variances.