TABLE 1

Characteristics of Patients Undergoing CCVR

VariableBaseline (n = 138)E1 (n = 50)PaE2 (n = 41)PaE3 (n = 87)PaE4 (n = 169)Pa
Age, mo, mean ± SD16.9 ± 14.717.8 ± 16.2.7217 ± 13.9.9517.2 ± 16.2.8819 ± 16.3.24
Weight, kg, mean ± SD10.2 ± 3.211.2 ± 4.7.1210.3 ± 3.5.8710.2 ± 4.9911.4 ± 9.8.26
Male sex, n (%)74 (54)29 (58).5925 (61).440 (46).26112 (66).02
Diagnosis, n (%).26.98.1.02
 ≤2-suture synostosis115 (83)37 (74)34 (83)63 (72)120 (71)
 Syndromic or ≥3 sutures19 (14)12 (24)6 (15)22 (25)45 (27)
 Other4 (3)1 (2)1 (2)2 (2)4 (2)
Procedure category, n (%).37.007.006<.001
 Fronto-orbital advancement118 (86)40 (80)27 (66)61 (70)110 (65)
 Posterior cranial vault reconstruction20 (14)10 (20)14 (34)26 (30)59 (35)
Previous craniofacial surgery32 (23)14 (28).510 (24).8724 (28).4639 (23).98
  • —, not applicable.

  • a Comparisons are presented between the baseline group and patients in each individual epoch by using Student’s t test for continuous variables or the χ2 test for categorical data.