TABLE 3

Neonatal Antimicrobial Stewardship Targets and Proposed SAAR Antimicrobial Agent Categories

Neonatal ASP TargetSAAR Agent CategoryAntimicrobials IncludedRoutes of AdministrationNHSN Units Included
Empiric treatment of late-onset sepsisVancomycinVancomycinIVII, II-III, III
Broad spectrum treatment of bacterial infectionsBroad spectrum antibacterial agentsPiperacillin and/or tazobactamIVII, II-III, III
Cefepime
Ertapenem
Meropenem
Imipenem and/or cilastatin
Prophylaxis and treatment of invasive candidiasisFluconazoleFluconazoleIV, oralII, II-III, III
Global or total antibiotic useAll antibacterial agentsAll antibacterial agents in AU optionIV, IM, oral, respiratoryII, II-III, III
Empiric treatment of early-onset sepsisAmpicillinAmpicillinIVAll
Cefotaxime, CeftazidimeCefotaximeIVAll
Ceftazidime
Empiric treatment of early-onset and late-onset sepsisAminoglycosidesGentamicinIVAll
Tobramycin
Amikacin
  • IM, intramuscular; IV, intravenous.