TABLE 3

Multivariable Logistic Regression Analysis of Infant Characteristics and Exposures Associated With Pharmacologically Treated NAS

ExposureaOR95% Confidence IntervalP
Infant characteristics
 Female0.880.65–1.19.42
 Low birth wt (<2500 g)1.080.70–1.68.71
 Preterm (<37 wk gestation)0.700.46–1.06.09
Opioid exposure type
 IR opioid1.651.01–2.69.04
 SR opioid2.061.41–3.02>.001
Additional licit and illicit exposures
 Tobacco1.130.70–1.83.59
 SSRIs1.170.70–1.94.54
 Benzodiazepine1.511.04–2.21.02
 THC0.770.54–1.09.14
 Cocaine1.380.81–2.36.22
 Gabapentin1.640.51–5.2.40
 Maternal HCV infection1.530.77–3.02.22
  • aOR, adjusted odds ratio.