TABLE 3

Prevalence of Bacteremia, Penicillin-Nonsusceptible Bacteremia, and Contaminated Blood Cultures Among Children Hospitalized With CAP

PredictorPrevalence, nBacteremia, n, % (95% CI)Penicillin-Nonsusceptible Bacteremia, n, % (95% CI)Contaminated Blood Culture, n, % (95% CI)
Single predictor
 WBC >2039021, 5.4 (3.5–8.1)3, 0.77 (0.26–2.2)2, 0.51 (0.14–1.9)
 ICU admission2529, 3.6 (1.9–6.7)3, 1.2 (0.41–3.4)4, 1.6 (0.62–4.0)
 Definite radiographic pneumonia122740, 3.3 (2.4–4.4)7, 0.57 (0.28–1.2)14, 1.1 (0.68–1.9)
 Complicated pneumoniaa1755, 2.9 (1.2–6.5)1, 0.57 (0.1–3.2)1, 0.57 (0.10–3.2)
Two predictors
 WBC >20 + ICU admission453, 6.7 (2.3–17.9)0, 0 (0–7.9)0, 0 (0–7.9)
 Complicated pneumonia + ICU admission473, 6.4 (2.2–17.2)1, 2.1 (0.38–11.1)0, 0 (0–7.6)
 Definite radiographic pneumonia + WBC >2031019, 6.1 (4.0–9.4)3, 0.97 (0.33–2.8)2, 0.65 (0.18–2.3)
 Definite radiographic pneumonia + ICU admission1499, 6.0 (3.2–11.1)3, 2.0 (0.69–5.8)2, 1.3 (0.37–4.8)
 Definite radiographic pneumonia + complicated pneumonia1595, 3.1 (1.4–7.1)1, 0.63 (0.11–3.5)1, 0.63 (0.11–3.5)
 WBC >20 + complicated pneumonia591, 1.7 (0.3–9.0)0, 0 (0–6.1)0, 0 (0–6.1)
Three predictors
 WBC >20 + definite pneumonia + complicated pneumonia551, 1.8 (0.32–9.6)0, 0 (0–6.5)0, 0 (0–6.5)
 WBC >20 + definite pneumonia + ICU admission323, 9.4 (3.2–24.2)0, 0 (0–10.7)0, 0 (0–10.7)
 WBC >20 + complicated pneumonia + ICU admission170, 0 (0–18.4)0, 0 (0–18.4)0, 0 (0–18.4)
 Definite pneumonia + complicated pneumonia + ICU admission433, 7.0 (2.4–18.6)1, 2.3 (0.41–12.1)0, 0 (0–8.2)
Four predictors
 WBC >20 + ICU admission + definite radiographic pneumonia + complicated pneumonia160, 0 (0–19.4)0, 0 (0–19.4)0, 0 (0–19.4)
  • Limited to the 1849 children with complete data available. Overall prevalence of bacteremia in the cohort was 2.4% (44 of 1849).

  • a Composite definition including moderate or large pleural effusion on initial chest radiograph and/or chest drainage procedure on initial or second hospital d.